A congratulatory balloon sways in the air behind Frances Arnold, 62, a 2018 Nobel Prize recipient originally from Pittsburgh, as she discusses her life achievements between advisory appointments with students, Monday, Oct. 8, 2018, in her office at the California Institute of Technology in Pasadena, Calif. Arnold, an Allderdice High School gradutate, is the first American women to win the Nobel Prize in Chemistry. (Jessie Wardarski/Post-Gazette)